Patch Clamp Amplifiers

Technology to shorten the pre-clinical development timeline   

Tecella Patch Clamp Amplifiers   

Since 2007 Tecella has supplied electrophysiology measurement systems that allow pharmaceutical researchers to rapidly screen drugs and medical compounds thereby accelerating and improving drug discovery.

Tecella offer a range of instruments for this fundamental technique; from the popular single channel Pico 2 to the 384-channel Apollo - designed for high throughput screening (HTS) systems.

In addition to electrophysiology, researchers working in electrochemistry, MEMS and other biotech fields can benefit from Tecella's highly scalable amplifier architectures and fully customisable software and hardware solutions.

PocketPatchSixteen channel USB-powered

The PocketPatch is a USB powered, small footprint device with an integrated digitiser and 16 built-in head stages,optimised for recording from ion channels embedded in planar lipid bilayers.

This next generation multi-channel patch clamp is built to the same exacting standards and offers the same low-noise performance as its predecessors. Originally designed to work with a custom biosensor array, the PocketPatch can be readily coupled to any custom bilayer array chip through a standard PCI Express connector interface.

Its compact size, and the ability to be controlled and powered by a single USB cable, reduces clutter and simplifies the lab setup. Tecella offers PCI Express adapter boards for connecting SMB or UMCC cables and can custom design other interface boards for your specific application.

Features

• Small footprint: 14.6 x 7.6 x 2.2 cm
• 16 channels (or 8 channel option)
• Controlled and powered by USB
• Fixed Bessel filter
• Independent JP offset control per channel
• Integrated digitiser
• Digital Trigger Outs x 4
• Integrated headstage with 2 gain values
• PCI Express connector (insert chip boards directly or cable adapter boards)
• SMB or UMCC cable adapter boards available

PocketPatch comes with the TecellaLab software for control and data acquisition, which is 100% compatible with the Triton model.

Pico 2Single channel USB-powered

An all-in-one voltage clamp, current clamp, digitiser and headstage

The Pico 2, from Tecella, is a fully-featured pocket sized, USB-powered low-noise patch clamp amplifier with integrated digitiser and headstage. It offers single channel recording, at sampling rates up to 40 kHz, and is small enough to be mounted directly on a manipulator.

Series resistance, fast capacitance, three slow capacitances, and a junction potential offset compensation circuit are included as standard. The unit is self-calibrating and a patented spread frequency compensation can automatically correct any arbitrary capacitance profile in seconds.

Multiple Picos can be connected to a single computer to record from multiple channels thanks to ExtenCell architecture.

Pico measures just 5.6" x 2.5" x 0.7" (14.2cm x 6.3cm x 1.8cm) and consumes less than 1 watt of power.

Software support includes TecellaLab acquisition software with export to ATF and tab formats, WinWCP from the University of Strathclyde, LabView VI, and C++ SDK/API for custom development and integration.

A PDF datasheet for the Pico 2 can be downloaded from the Documents tab above.

Triton+2 to 16 channels

Data from Patch Clamp or Bilayer experiments can be recorded in up to 16 channels simultaneously at a 20 kHz sampling rate with Tecella's Triton+.

This robust, low noise compact instrument is perfect for benchtop use, or can easily be integrated into a complete HTS system.

Features include: integrated stimuscope digitiser, embedded model cells, and analogue compensations. Custom options are available too, just contact us for details.

Flex8 to 96 channels

The Flex is a multi-channel patch clamp amplifier configurable from 8 to 96 channels in 8 channel steps.

It offers a comprehensive range of standard and customisable features:
 

Impulse8 to 64 channel MEA amplifier

Impulse is a new compact and low noise 64-channel microelectrode array amplifier designed to work with a variety of probes. A Windows DLL is available for custom development and OEM integration.

Jet16 to 128 channels

HQHT (high quality high throughput) recordings from up to 128 channels simultaneously are enabled by the Jet from Tecella.

Jet is perfect for high channel count designs and can easily be system integrated into a complete HTS system. It can even be used as a stand alone benchtop device.

Features include: integrated stimuscope digitiser, embedded model cells, and analogue compensations. Custom options are available too, just contact us for details.

Apollo48 to 384 channels

Tecella created the world's first 384-channel patch clamp amplifier, enabling researchers to discover new possibilities in HQHT (high quality high throughput) data recording.

This low noise, low power, and low heat instrument is perfect for extremely high channel count designs. Apollo can easily be system integrated into a complete HTS system, keeping the amount of space allotted for the amplifier to a minimum. It can even be used as a stand alone benchtop device due to its small footprint.

Features include: integrated stimuscope digitiser, embedded model cells, and analogue compensations. Custom options are available too, just contact us for details.

More details on these products can be found in the Tecella Product Brochure downloadable from the Documents tab above, or via their website.

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